“For the first time, scientists have used the gene-editing technique CRISPR to try to edit a gene while the DNA is still inside a person’s body. Previous research has demonstrated that biofortification of rice can help prevent blindness, weakened immune systems and other health problems associated with vitamin A deficiency, which is especially prevalent among children in developing nations.”Ĥ March, 2020 In A 1st, Scientists Use Revolutionary Gene-Editing Tool To Edit Inside A Patient Their research… demonstrated that CRISPR-Cas9 can be successfully used to biofortify rice with carotenoid, a precursor to the essential nutrient vitamin A. “A team of California plant scientists has taken a CRISPR-Cas9 approach to develop more nutritious varieties of rice. Also Joan Conrow New study shows CRISPR can be applied to produce biofortified rice Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9. The scientists say they will know within a few weeks if the treatment is working and safe, and plan to test it on additional patients if so.”Ĥ March, 2020 Oliver Xiaoou Dong, et al.
They are attempting to treat an inherited form of blindness called Leber congenital amaurosis, the Associated Press reports. “ Cambridge, Massachusetts–based Editas Medicine and Dublin-based Allergan announced today (March 4) that doctors at the Casey Eye Institute of Oregon Health & Science University in Portland used CRISPR gene editing inside a patient for the first time. The deal, which President Vladimir Putin ordered in December, aims to accelerate Russia’s $1.6 billion program to create 30 new varieties of genetically modified crops and animals by 2027.”Ĥ March, 2020 Jeff Akst First Patient Receives In Vivo CRISPR Editing ĭoctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy. “Russia’s oil giant Rosneft and the Russian government will join forces to develop gene-editing technology, according to a government decree published Wednesday.
In a strongly worded commentary, the European Academies Science Advisory Council (EASAC) said the current EU regulations are “no longer fit for purpose” and warned of serious ramifications if the rules are not eased to allow new plant breeding techniques to move forward.”Ĥ March, 2020 Alexander Avilov Rosneft Joins Russia’s Gene-Editing Tech Program “A top European science council calling is demanding a “radical reform of the legal framework” that regulates genetically modified organisms (GMOs) in the European Union. It will be updated as developments warrant.ĥ March, 2020 Joan Conrow Top European science council demands ‘radical’ GMO regulatory reform and It is not complete or encyclopedic, but eclectic, focused primarily on CRISPR, and, we hope, illuminating.
This compilation brings together a list of salient events and media coverage over the last three decades. It can be very hard to keep up, even for those following closely. Hardly a day goes by without new reports of advances in gene editing. Note: This timeline was last updated on March 10, 2020. Senior Fellow, Information Technology & Innovation Foundation For example, Japan, which has no commercialized GMOs, is emerging as a leader in the introduction of gene edited crops. How this will effect gene editing regulations is also unclear. It’s somewhat true that countries with product-based regulation have more crops approved and the approval process is more streamlined, but there are contradictions. For example, Brazil and Argentina have emerged as GMO super powers using different regulatory concepts, while there is no GMO commercial cultivation in Japan, North Korea, and the Russian Federation, which employ product-based regulations. It’s not clear how much this distinction matters. Transgenic crops and animals (aka GMOs) are product regulated in many countries including the US and Canada, while the EU, India, China and others regulate based on how the product is made. There is almost an equal number of countries with product- and process-based regulations. Whether regulations are based on the genetic process used to create the trait (conventional, mutagenesis, transgenesis, gene editing, etc.) or the final product.
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